Lenvatinib

• Increased blood pressure
• Monitor your blood pressure regularly and record it down. Inform your doctor if you notice an increasing trend.
• Feeling tired and lack of energy
• Do not drive or operate machinery when you feel tired
• Diarrhea
• Drink plenty of clear fluids to replace those lost (two litres everyday)
• Decreased appetite, nausea or vomiting
• Take small, frequent meals throughout the day
• Mouth sores or ulcers
• Rinse your mouth after every meal using an alcohol-free mouthwash or salt water
• Brush your teeth with a soft toothbrush
• Voice hoarseness
• Stomach discomfort
• Weight loss
• Joint or muscle ache, headache
• You may take paracetamol when necessary to help with this
• Palms of the hands or soles of the feet may become numb, sore, red or dr
• Moisturize these areas daily
• Avoid wearing tight-fitting shoes

 If you experience any of the following symptoms, you should stop your medication and see your healthcare professional immediately.

• Abnormal heartbeat, chest pain or shortness of breath
• Very bad swelling of hands, feet or lower legs
• Dark urine or light coloured stools
• Yellowing of your eyes or skin
• Very bad diarrhea, nausea, vomiting or stomach pain
• Pain while urinating
• Abnormal muscle cramps or numbness
• Unusual weakness, tiredness or lightheadedness
• Unusual bleeding, bruising, black sticky stools or blood in urine
  
• Symptoms of a drug allergy including one or more of the following:
  
• Swollen face/eyes/lips/tongue
  
• Difficulty in breathing
• Itchy skin rashes over your whole body
  

​Inform your healthcare professional if:

• You are allergic to this medication or any of the other ingredients of this medication
• You or your partners becomes pregnant or is planning for pregnancy
  
• You should use effective birth control during and for at least one month after stopping treatment.
• You are breastfeeding
• Do not breastfeed during and for at least two weeks after stopping treatment
• You are taking any other medications, including supplements, traditional medications, and herbal remedies
• You have any other medical conditions (e.g. heart problems, high blood pressure)
• You have any recent or upcoming surgery

​Avoid medications that are known to interfere with heart rhythms.