MBBS, M Med (Family Med), FCFP(S), MCI (NUS), FAMS
Clin A/P (Dr) Tan has been a Family Physician cum senior consultant for the past 15 years. He is a Fellow with the College of Family Physicians Singapore and Academy of Medicine who graduated as one of the six pioneer group of clinicians in the Master in Clinical Investigations in NUS. Since his appointment as Director of Research in SHP in 2012, A/P Tan has been coaching medical and nursing undergraduates, Family Medicine Residents and Family Physicians in Family Medicine Research. His research interests focus on improving person-centred care via technology and innovation. A/P Tan is also the recipient of the Humanity Award in 2006 for research relating to SARS, SingHealth Excellence Award for Clinician in 2012. He is the first family physician to receive the NMRC Clinician Innovator Development Award in 2019 to develop a novel internet of thing system to promote smoking cessation. He has published more than 120 papers in peer-reviewed journals and received awards for oral and poster presentations at various WONCA and Family Medicine Conferences.
• Tan Hwee Mian Jane, Tan Mui Suan, Chang Zi Ying, Tan Kee Tung, Ee Guan Liang Adrian, Ng Chee Chin David, William Hwang, Koh Yi Ling Eileen, Low Yan Ping Sarah, Tan Ngiap Chuan. The impact of COVID-19 pandemic on the health-seeking behaviour of an Asian population with acute respiratory Infections in a densely populated community. Accepted for publication in BMC Public Health. 2021 JIF: 2.837• Moey KSP, Ang TWA, Ee GLA, Ng CCD, Ng CWM, Teo SHS, Tay EG, Tan NC. What are the measures taken to prevent COVID-19 infection among healthcare workers? A retrospective study in a cluster of primary care clinics in Singapore. Accepted for publication in BMJ Open 2021 JIF: 2.496• Ruiyang Zou, Sau Yeen Loke, Veronique Kiak-Mien Tan, Swee Tian Quek, Pooja Jagmohan, Yew Chung Tang, Preetha Madhukumar, Benita Kiat-Tee Tan, Wei Sean Yong, Yirong Sim, Sue Zann Lim, Eunice Png, Shu Yun Sherylyn Lee, Mun Yew Patrick Chan, Teng Swan Juliana Ho, Boon Kheng James Khoo, Su Lin Jill Wong, Choon Hua Thng, Bee Kiang Chong, Yik Ying Teo, Heng-Phon Too, Mikael Hartman, Ngiap Chuan Tan, Ern Yu Tan, Soo Chin Lee, Lihan Zhou, Ann Siew Gek Lee. Development of a novel microRNA panel for classification of abnormal mammograms for breast cancer. Cancers. 2021;13, 2130.https://doi.org/10.3390/cancers13092130. JIF: 6.126• Zheng Lifeng, Agnes Ngoh Soh Heng, Tan Ngiap Chuan. Clinician perspectives on a culturally adapted patient decision aid concerning maintenance therapy for asthma Journal of Asthma. 2021. DOI: 10.1080/02770903.2021.1923736. JIF: 1.849• Samuel Teong Huang Chew, Geetha Kayambu, Charles Lew, Tze Pin Ng, Fangyi Ong, Jonathan Tan, Ngiap Chuan Tan, Shuen-Loong Tham. Singapore Multidisciplinary Consensus Recommendations on Muscle Health in Older Adults: Assessment and Multimodal Targeted Intervention Across the Continuum of Care. BMC Geriatrics. BMC Geriatrics (2021) 21:314. https://doi.org/10.1186/s12877-021-02240-8. JIF: 3.077• Shawn Goh Kuan Liang, Lee Cia Sin, Gerald Koh Choon Huat, Ng Ling Ling, Ang Seng Bin, Christina Oh Mei Ai, Lin Yongqin, Wei Yuan, Charles Zheng Qishi, Tan Ngiap Chuan. Evaluating the Effectiveness and Utility of a Novel Culturally-Adapted Telemonitoring system in improving the Glycaemic Control of Asians with Type-2 Diabetes Mellitus: A Mixed Method Study Protocol. Trials. 2021. 22:305. https://doi.org/10.1186/s13063-021-05240-6 JIF: 1.975• Syarafina Hasnan, Tan Ngiap Chuan. Multi-Domain Narrative Review of Vaccine Hesitancy in Childhood. Vaccines. Apr 21. Vol 39 (14). 1910-1920. JIF: 3.143.• Wang ZS, Yap J, Koh YLE, Chia SY, Nivedita N, Ang TWA, Goh SCP, Lee CS, Tan LLJ, Ooi CW, Seow M, Yeo KK, Chua SJT, Tan NC. Predicting Coronary Artery Disease in Primary Care: Development and Validation of a Diagnostic Risk Score for Major Ethnic Groups in Southeast Asia. J Gen Intern Med. 2021 Mar 26. doi: 10.1007/s11606-021-06701-z. Epub ahead of print. PMID: 33772443. JIF: 4.597• Ian Kwong Yun Phoon, Yi Ling Eileen Koh, Xiaoxuan Guo, Sankari Usha, Ngiap Chuan Tan. Compatibility between Fasting and Random LDL-Cholesterol Tests in Asians. Scientific Reports. 2021 Mar 19; 11(1): 6478. JIF: 3.998• Julia Sok Wei Yuen, Tsang Yew Tay, Ning Gao, Nian Qin Tho, Tan Ngiap Chuan. Development of a decision aid to support colorectal cancer screening: Perspectives of Asians in an endemic urban community: A Qualitative Research Study. BMC Med Inform Decis Mak. 2021 Mar 6;21(1):86. doi: 10.1186/s12911-021-01404-1. JIF: 2.580• Felicia Clara Tan Jun Hui, I Gusti Ngurah Prawira Suartha Oka, Tan Ngiap Chuan. The Association between Self-Efficacy and Self-Care in Essential Hypertension: A Systematic Review. BMC Family Practice (2021) 22:44. https://doi.org/10.1186/s12875-021-01391-2. JIF: 2.520• Bilger M, Shah M, Tan NC, Tan CYL, Bundoc FG, Bairavi J, Finkelstein EA. Process- and Outcome-Based Financial Incentives to Improve Self-Management and Glycemic Control in People with Type 2 Diabetes in Singapore: A Randomized Controlled Trial. Patient. 2021 Jan 25. doi: 10.1007/s40271-020-00491-y. Epub ahead of print. PMID: 33491116. JIF: 2.673• M Meyappan, ALW Siong, LY Tan, SFI Tan, PY Ho, YJ Poh, NC Tan. Development of a Novel Gout Treatment Patient Decision Aid by Patient and Physician: A Qualitative Research Study. Health Expectations. 2021 doi.org/10.1111/hex.13184. JIF: 2.847• Fang, H.S.A., Gao, Q., Lee, M.L, W Hsu, NC Tan. LDL-cholesterol change and goal attainment following statin intensity titration among Asians in primary care: a retrospective cohort study. Lipids Health Dis 20, 2 (2021). https://doi.org/10.1186/s12944-020-01427-z. JIF: 2.906• Lim JE, Wong WT, Teh TA, Lim SH, Allen JC Jr, Quah JHM, Malhotra R and Tan NC (2021) A Fully-Immersive and Automated Virtual Reality System to Assess the Six Domains of Cognition: Protocol for a Feasibility Study. Front. Aging Neurosci. 12:604670. doi: 10.3389/fnagi.2020.604670. JIF: 3.633• Wang Y, Tan NC, Jafar TH. Ethnic Variation, Socioeconomic Status, and Factors Associated with Cardio-metabolic Multi-morbidity among Uncontrolled Hypertension in Multi-ethnic Singapore. J Hum Hypertens. 2021 Apr 9, doi: 10.1038/s41371-020-00457-5. Epub ahead of print. PMID: 33837292. JIF: 1.960• Huang Chew ST, Tan NC, Cheong M, Oliver J, Baggs G, Choe Y, How CH, Chow WL, Ling Tan CY, Kwan SC, Husain FS, Low YL, Thu Huynh DT, Tey SL. Impact of specialized oral nutritional supplement on clinical, nutritional, and functional outcomes: a randomized, placebo controlled trial in community-dwelling older adults at risk of malnutrition, Clinical Nutrition. 2020 Oct 15:S0261-5614(20)30543-4. doi:doi.org/10.1016/j.clnu.2020.10.015. Epub ahead of print. PMID: 33268143. JIF: 6.402• Hwang SJ, Tan NC, Yoon S, et al. Perceived barriers and facilitators to chronic kidney disease care among patients in Singapore: a qualitative study. BMJ Open 2020;10:e041788. doi: 10.1136/bmjopen-2020-041788. JIF: 2.376• M Cheong, STH Chew, J Oliver, G Baggs, YL Low, CH How, NC Tan, DTT Huynh, SL Tey. Nutritional Biomarkers and Associated Factors in Community-Dwelling Older Adults: Findings from the SHIELD Study. Nutrients 2020, 12, 3329; doi:10.3390/nu12113329. JIF: 4.171• Chew THS, Tan NC, Cheong M, Oliver J, Baggs G, Choe Y, How CH, Chow WL, Ling Tan CY, Kwan SC, Husain FS, Low YL, Thu Huynh DT, Tey SL. Impact of specialized oral nutritional supplement on clinical, nutritional, and functional outcomes: a randomized, placebo controlled trial in community-dwelling older adults at risk of malnutrition, Clinical Nutrition. 2020 Oct 15:S0261-5614(20)30543-4. doi:doi.org/10.1016/j.clnu.2020.10.015. PMID: 33268143. JIF: 6.402• Lim CC, Ang ATW, Kadir HBA, Lee PH, Goh BQ, Harikrishnan S, Kwek JL, Gan SSW, Choo JCJ, Tan NC. Short-Course Systemic and Topical Non-Steroidal Anti-Inflammatory Drugs: Impact on Adverse Renal Events in Older Adults with Co-Morbid Disease. Drugs Aging. 2020 Nov 30. doi: 10.1007/s40266-020-00824-4. Epub ahead of print. PMID: 33251568. • Accepted13 November 2020, Published30 November 2020. JIF: 2.820• Wang Y, Tan NC, Jafar TH. Ethnic Variation, Socioeconomic Status, and Factors Associated with Cardio-metabolic Multi-morbidity among Uncontrolled Hypertension in Multi-ethnic Singapore. J Hum Hypertens. 2021 Apr 9, doi: 10.1038/s41371-020-00457-5. Epub ahead of print. PMID: 33837292. JIF: 1.960• Boo AYY, Koh YLE, Hu PL, Tan NC. Prevalence and factors associated with false hyperkalaemia in Asians in primary care: a cross-sectional study (the Unlysed Hyperkalaemiathe Unseen Burden (UHUB) study). BMJ Open 2020;10:e033755. doi:10.1136/ bmjopen-2019-033755. JIF: 2.376• Pei Lin Hu; Cynthia Yan-Ling Tan; Ngoc Hoang Long Nguyen, Ryanne Wu; Juliana Bahadin; Nivedita Vikas Nadkarni; Ngiap Chuan Tan. Integrated care teams in primary care improve clinical outcomes and care processes in patients with non-communicable diseases. SMJ. Accepted for publication: 17 Jul 2020. JIF: 1.359• Tan Ngiap Chuan, Eileen Koh Yi Ling, Sabrina Wee. Assessment and Stratification of Self-Care Profile in Patients with Essential Hypertension. SMJ. Accepted for publication: 14 Aug 20. JIF: 1.359• Facilitators and barriers to post-partum diabetes screening among mothers with a history of gestational diabetes mellitus - a qualitative study from Singapore. SH Sunny, R Malhotra, SB Ang, DCS Lim, AYS Tan, BYM Soh, CXY Ho, M Gostelow, MLP Tsang, SSH Lock, SY Kwek, JYT Lim, K Vijakumar, NC Tan. Frontiers in Endocrinology. 28 Aug 2020;11:602.• The association between beliefs and adherence to inhaled controller medication among older adults with asthma: a cross-sectional study in primary care. C Liu, CW Tham, JD Roza, BY Chong, EYL Koh, NC Tan. Patient Preference and Adherence. 2020 Aug;14:1351–1359. Published 2020 Aug 4.• Psychometric Evaluation of a Patient Satisfaction Survey Questionnaire to Assess Advanced Practice Nurse Ambulatory Service in Primary Care. Lee CF, EYL Koh, Wang X, Wong PNF, Ngoh SHA, Z M Mohtar, Lian LG, Ang KW, Tan NC. Journal of Nursing Management. 2020; 00; 1-8. DOI: doi.org/10.1111/jonm.13072.• Prevalence and factors influencing adherence to anti-hypertensive medications among adults with hypertension in an Asian developed community: a cross-sectional study. G Kang, EYL Koh, Tan NC. Proceedings of Singapore Healthcare. 10 Jun 20. Epub.• Validation of the kidney failure risk equation for end-stage kidney disease in Southeast Asia. Y Wang, FNHL Nguyen, JC Allen, JLL Quan, NC Tan, TH Jafar. BMC Nephrology (2019) 20:111.• Rates and predictors of nonadherence to postophthalmic screening tertiary referrals in patients with type 2 diabetes. Sia JT, Gan ATL, Soh BP,Fenwick E, Quah J, Sahil T, Tao Y, Tan NC, Sabanayagam C, Lamoureux EL,Man REK. Trans Vis Sci Tech. 2020 May;9(6):15.• Building a Longitudinal National Integrated Cardiovascular Database. Yeo KK, Ong HY, Chua TSJ, Lim ZJ, Yap J, Ho H, Jaufeerally F, Tong KL, Kojodjojo P, Wong HB, Heng D, Tan K, Richards A, Teoh K, Sin K, Tan NC, Lee SBM, Lim T, Ta A, Liok E, Lau YH, Gao F, Liman C, Sakar J, Sahlen A, Koh TH, Chan MY. Circ Rep 2020 Jan; 2: 33 – 43.• Will the future BE POSITIVE? Early Life Experience as a Signal to the Developing Brain Pre School Entry. A Rifkin, K Khng, P Cheung, S Tsotsi, H Sun, F Kwok, Y Yu, H Xie, Y Yang, M Chen, DCC Ng, PL Hu, NC Tan. 2019 Oct. Learning: Research and Practice. 5 (2) pg 99-125.• Physical activity and sedentary behaviour of ambulatory older adults in a developed Asian community: a cross-sectional study. LP Ng, EYL Koh, NC Tan. Singapore Medical Journal. 2020 Mar. 61(5); 266-271.• The prevalence and factors associated with sarcopenia among community living elderly with type 2 diabetes mellitus in primary care clinics in Malaysia. Sazlina S-G, Lee PY, Chan YM, A. Hamid MS, Tan NC. (2020) PLoS ONE. 2020 May. 15(5): e0233299.• Cultural adaptation of a patient decision-aid for insulin therapy. NC Tan, AKL Koong, IKY Phoon, SZ Wang, M Paulpandi, YK Lee, J Furler, J Car, CJ Ng. BMJ Open 2020 Mar;10:e033791.• Roles and recommendations from primary care physicians towards managing low-risk breast cancer survivors in a shared-care model with specialists in Singapore - a qualitative study. RWY Fok, LL Low, HMJ Quah, F Vasanwala, SG Low, LL Soh, F Mohamad, KWJ Loh, YL Soong, Y Ke, A Chan, NC Tan. Family Practice. 2020 Feb. 1-7.• Assessment of willingness to Telemonitoring interventions in patients with type 2 diabetes and/or hypertension in the public primary healthcare setting. DYE Sin, X Guo, DWW Yong, TY Qiu, PKS Moey, M-R Falk, NC Tan. BMC Medical Informatics and Decision Making. (2020) 20:11.• Interaction between Antibiotic Resistance, Resistance Genes and Treatment Response for Urinary Tract Infections in Primary Care. H Ho, MX Tan, M Chen, TY Tan, SH Koo, A Koong, LP Ng, PL Hu, KT Tan, P Moey, E Koh, CS Wong, D Lye, NC Tan. JClin Microbiol57:e00143-19.• The self-care profiles and its determinants among adults with hypertension in primary health care clinics in Selangor, Malaysia. Salim H, Lee PY, Sazlina SG, Ching SM, Mawardi M, Shamsuddin NH, Ali H, Ismail HA, Tan NC. (2019) PLoS ONE 14(11):e0224649.• Factors associated with muscle mass in community dwelling older people in Singapore: Findings from the SHIELD study. Tey SL, Chew STH, How CH, Yalawar M, Baggs G, Chow WL, Cheong M, Ong RHS, Husain FS, Kwan SC, Tan CYL, Low YL, Tan NC, Huynh DTT. (2019) PLoS ONE. 2019;14(10):e0223222. Published 2019 Oct 9.• To give or not to give: no dearth of explicit guidelines on potentially inappropriate prescribing of non-steroidal anti-inflammatory drugs to older adults. Lim CC, Tan NC, Ang ATW, Quek NWS, Choo JCJ. Internal Medicine Journal 2019;49(11) 1461–1462.• Association of baseline hand grip strength and annual change in hand grip strength with mortality among older people. R Malhotra, MI Tareque, Tan NC, S Ma. Archives of Gerontology and Geriatrics. 2020 Jan-Feb. 86; 103961.• Blood pressure goal attainment in multi-ethnic Asian patients with hypertension and dyslipidaemia in primary care. Koh KH, Goh CC, Goh PSC, Koh EYL, Tan NC. SMJ 2019.• Virtual Reality for Screening of Cognitive Function in Older Persons: Comparative Study. SIL Chua, Tan NC, Wong WT, JC Allen Jr, Quah JHM, R Malhotra, T Østbye. J Med Internet Res 2019;21(8):e14821).• Adiposity measures and pre - diabetes or diabetes in adults with hypertension in Singapore polyclinics. Y Wang, RM Shirore, C Ramakrishnan, NC Tan, TH Jafar. J Clin Hypertension (Greenwich). 2019;21(7):953-962.• The Use of Wireless, Smartphone App–Assisted Home Blood Pressure Monitoring Among Hypertensive Patients in Singapore: Pilot Randomized Controlled Trial. EW Moon, NC Tan, JC Allen, TH Jafar. JMIR Mhealth Uhealth 2019;7(5):e13153. Published 2019 May 28.• A Mobile Lifestyle Management Program (GlycoLeap) for People With Type 2 Diabetes: Single-Arm Feasibility Study. D Koot, PSC Goh, RSM Lim, Y Tian, TY Yau, NC Tan, EA Finkelstein. JMIR Mhealth Uhealth. 2019;7(5):e12965). Published 2019 May 24.• Review of the quality of printed patient education materials on asthma available in primary care in Singapore. CY Phua, L Zheng, NC Tan, WE Tang. Journal of Asthma. 2020 Jul. 57(7); 787-798.• Asthma care based on Chronic Care Model in an aging Asian community. LF Zheng, EYL Koh, U Sankari and NC Tan. npj Primary Care Respiratory Medicine. 2019;29(1):16. Published 2019 May 3.• Prevalence of and factors associated with sarcopenia among multi-ethnic ambulatory older Asians with type 2 diabetes mellitus in a primary care setting. FY Fung, EYL Koh, R Malhotra, T Ostbye, PY Lee, SS Ghazali and NC Tan. BMC Geriatrics (2019) 19:122. Published 2019 Apr 29.• Accuracy of urinary symptoms and urine microscopy in diagnosing urinary tract infection in women. Tan NC, Koong AYL, Ng LP, Hu PL, Koh EYL, Tan KT, Moey PKS, Tan MX, Wong CS, Tan TY, Ho HJA, Chen MI. Fam Pract. 2019 Jul 31;36(4):417-424. JIF: 1.675• Achieving triple treatment goals in multi-ethnic Asian patients with type 2 diabetes mellitus in primary care. Goh CC, Koh KH, Goh SCP, Koh YLE, Tan NC. Malays Fam Physician. 2018;13(2);10–18.• Patients on levothyroxine replacement in the community: association between hypothyroidism symptoms, co-morbidities and their quality of life. Tan NC, Chew RQ, Subramanian RC, Sankari U, Koh YLE, Cho LW. Fam Pract. Jul 2018.• Health outcomes of patients with chronic disease managed with a healthcare kiosk in primary care: protocol for a pilot randomised controlled trial. Ng G, Tan SW, Tan NC. BMJ Open. 2018 Mar 23;8(3):e020265.• Management of hypertension and multiple risk factors to enhance cardiovascular health in Singapore: The SingHypertension cluster randomized trial. Jafar TH, Tan NC, Allen JC, Finkelstein EA, Goh P, Moey P, Quah JHM, Hwang SW, Bahadin J, Thiagarajah AG, Chan J, Kang G, Koong A. Trials. 2018 Mar 14;19(1):180.• Late Breaking Abstract-Predictive value of FeNO in patients with non-specific respiratory symptoms: a randomised controlled trial. Price D, Buhl R, Copland A, Freeman D, Godley C, Jones KG, Lapperre T, Law L, Mcgarvey L, Ohta K, Ryan D, Syk J, Tan NC, Tan TL, Thomas M, Chan A. European Respiratory Journal. 2017 Dec. 50(61).• An exhaled carbon monoxide self-monitoring device linked to social media to support smoking cessation: A proof of concept pilot study. Tan NC, Mohtar ZBM, Koh YLE, Sankari U, Tay HCD, Yu S, Tan BWW. Proceedings of Singapore Healthcare. 2018 Feb. [epub].• Evaluation of a Hybrid undergraduate dermatology training workshop during Family Medicine clerkship. Mitesh S, Tan NC, Koh YLE. The Singapore Family Physician. 2018 Jan; 44(1):39-45.• Factors Associated with Chronic Kidney Disease and Their Clinical Utility in Primary Care Clinics in a Multi-Ethnic Southeast Asian Population. Lew QLJ, Allen JC, Nguyen F, Tan NC, Jafar TH. Nephron. 2017 Dec 15. (epub)• Sickness certification in Singapore’s public primary healthcare system: A cross-sectional analysisF. DCC Ng, YJ Lew, EYL Koh, VH Nguyen, HB Wong, L James and NC Tan. Proceedings of Singapore Healthcare. 2017 Dec. (Epub).• Trial to Incentivise Adherence for Diabetes (TRIAD): study protocol for a randomised controlled trial. Bilger M, Shah M, Tan NC, Howard KL, Xu HY, Lamoureux EL, Finkelstein EA. Trials. 2017 Nov 17;18(1):551.• Test-retest reliability of the Mandarin versions of the Hypertension Self-Care Profile instrument. Medicine (Baltimore). Ngoh SHA, Lim HWL, Koh YLE, Tan NC. 2017 Nov;96(45):e8568.• Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images from Multiethnic Populations with Diabetes. Ting DSW, Cheung CY, Lim G, Tan GSW, Quang ND, Gan A, Hamzah H, Garcia-Franco R, San Yeo IY, Lee SY, Wong EYM, Sabanayagam C, Baskaran M, Ibrahim F, Tan NC, Finkelstein EA, Lamoureux EL, Wong IY, Bressler NM, Sivaprasad S, Varma R, Jonas JB, He MG, Cheng CY, Cheung GCM, Aung T, Hsu W, Lee ML, Wong TY. JAMA. 2017 Dec 12;318(22):2211-2223.• 'Bilingual Text With or Without Pictograms Improves Elderly Singaporeans’ Understanding of Prescription Medication Labels. Malhotra R, Bautista MAC, Tan NC, Tang WE, Tay SCS, Tan ASL, Pouliot A, Saffari SE, Lye CC, Vaillancourt R. The Gerontologist. 2017 Nov (ePub ahead of print).• Comparative immunogenicity and safety of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine and 4vHPV vaccine administered according to two- or three-dose schedules in girls aged 9-14 years: Results to month 36 from a randomized trial. Leung TF, Liu AP, Lim FS, Thollot F, Oh HML, Lee BW, Rombo L, Tan NC, Rouzier R, De Simoni S, Suryakiran P, Hezareh M, Thomas F, Folschweiller N, Struyf F. Vaccine. 2018 Jan 2;36(1):98-106.• Fractional exhaled nitric oxide as a predictor of response to inhaled corticosteroids in patients with non-specific respiratory symptoms and insignificant bronchodilator reversibility: a randomised controlled trial. Price DB, Buhl R, Chan A, Freeman D, Gardener E, Godley C, Gruffydd-Jones K, McGarvey L, Ohta K, Ryan D, Syk J, Tan NC, Tan T, Thomas M, Yang S, Konduru PR, Ngantcha M, d'Alcontres MS, Lapperre TS. Lancet Respir Med. 2018 Jan;6(1):29-39.• Longitudinal trends in HbA1c and associations with comorbidity and all-cause mortality in Asian patients with type 2 diabetes: A cohort study. Luo M, Lim WY, Tan CS, Ning Y, Chia KS, van Dam RM, Tang WE, Tan NC, Chen R, Tai ES, Venkataraman K. Diabetes Res Clin Pract. 2017 Nov;133:69-77.• Assessing oral medication adherence among patients with type 2 diabetes mellitus treated with polytherapy in a developed Asian community: a cross sectional study. Lee CS, Tan JHM, Sankari U, Koh YLE, Tan NC. BMJ Open. 2017;7:e016317. • What is the test-retest reliability of the Malay version of the Hypertension Self-Care Profile self-efficacy assessment tool? A validation study in primary care. Seow KC, Mohamed Yusoff D, Koh YLE, Tan NC. BMJ Open. 2017 Sep 6;7(9):e016152.• Factors associated with impaired color vision without retinopathy amongst people with type 2 diabetes mellitus: a cross-sectional study. Tan NC, Yip WF, Kallakuri S, Sankari U, Koh YLE. BMC Endocr Disord. 2017 Jun 2;17(1):29.• Smoking literacy amongst adult Asian asthma patients in primary care. Ngoh ASH, Chen ZJ, Tai BC, Teo SSH, Tan NC. Proceedings of Singapore Healthcare 2017 Dec; 26(4): 235-240.• Deprescribing: What are the views and factors influencing this concept among patients with chronic diseases in a developed Asian community? WL Ng, MZW Tan, EYL Koh, NC Tan. Proceedings of Singapore Healthcare. 2017 Sep; 26(3): 172-179.• A cross-sectional study of gender differences in lifestyle behavior and usage of medications among community-dwelling Asians towards achieving their LDL-Cholesterol treatment goals. NC Tan, EYL Koh, CC Goh, PSC Goh and KH Koh. Proceedings of Singapore Healthcare. 2017 Sep; 26(3): 158-165.• Primary hypothyroidism in the community: Lower daily dosages of levothyroxine replacement therapy for Asian patients. Tan NC, Chew RQ, Koh YL, Subramanian RC, Sankari U, Meyappan M, Cho LW. Medicine (Baltimore). 2017 Feb;96(7):e6145.• Do primary care physicians use the 5As in counselling obese patients? A qualitative study. JJML Lee, YC Tung, KP Tai, SA Tay, SJ Cheng, SB Ang, NC Tan. Proceedings of Singapore Healthcare. 2017 Sep; 26(3):144-149.• Association between asthma control and asthma cost: Results from a longitudinal study in a primary care setting. Nguyen HV, Nadkarni NV, Sankari U, Mital S, Lye WK, Tan NC. Respirology. 2017 Apr;22(3):454-459.• The utility of diabetes risk score items as predictors of incident type 2 diabetes in Asian populations: An evidence-based review. Hu PL, Koh YL, Tan NC. Diabetes Res Clin Pract. 2016 Dec;122:179-189.• Cost-effectiveness of a National Telemedicine Diabetic Retinopathy Screening Program in Singapore. Nguyen HV, Tan GS, Tapp RJ, Mital S, Ting DS, Wong HT, Tan CS, Laude A, Tai ES, Tan NC, Finkelstein EA, Wong TY, Lamoureux EL. Ophthalmology. 2016 Dec;123(12):2571-2580.• Health-related quality of life of older Asian patients with multimorbidity in primary care in a developed nation. Quah JH, Wang P, Ng RR, Luo N, Tan NC. Geriatr Gerontol Int. 2017 Oct;17(10):1429-1437. doi: 10.1111/ggi.12881. Epub 2016 Aug 31. PubMed PMID: 27576513.• The effect of the intensity of lipid-lowering medications on the LDL-Cholesterol treatment goals of Asian patients with dyslipidemia in primary care. Tan NC, Goh CC, Goh P, Koh YL, Koh KH. J of Clin Pharm and Therapeutics. 2016 Dec;41(6):677-683.• Sleep time and pattern of adult individuals in primary care in an Asian urbanized community: A cross-sectional study. Tan NC, Tan MS, Hwang SW, Teo CC, Lee ZK, Soh JY, Koh YL, How CH. Medicine (Baltimore). 2016 Aug;95(35):e4749.• Normative values of hand grip strength for elderly Singaporeans aged 60 to 89 years: A cross sectional study. Malhotra R, Ang S, Allen JC, Tan NC, Ostbye T, Saito Y, Chan A. JAMDA. 1 September 2016. 17(9): 864.e1 – 864.e7.• Orthostatic hypotension: prevalence and associated risk factors among the ambulatory elderly in an Asian population. Zhu QO, Tan GCS, Tan HL, Wong GR, Joshi CS, Cuttilan RA, Sng KJ, Tan NC. Singapore Med J. 2016. 57(8): 444-451. doi: 10.11622/smedj.2016135.• Management of hypertension and multiple risk factors to enhance cardiovascular health - a feasibility study in Singapore polyclinics. Jafar TH, Tan NC, Allen JC, Pradhan SS, Goh P, Tavajoh S, Keng FM, Chan J. BMC Health Serv Res. 2016 Jul 8;16:229. doi: 10.1186/s12913-016-1491-6. PubMed PMID: 27391818; PubMed Central PMCID: PMC4938988.• The impact of direct observed therapy on daily living activities, quality of life and socioeconomic burden on patients with tuberculosis in primary care in Singapore. Lee HK, Teo SSH, Barbier S, Tang SC, Yeo GH, Tan NC. Proceedings of Singapore Healthcare. 2016 Dec;25(4):235-242.• HbA1c, Systolic Blood Pressure Variability and Diabetic Retinopathy in Asian Type 2 Diabetes. Foo V, Quah J, Cheung G, Tan NC, Lin MZ, Chan CM, Lamoureux E, Wong TY, Tan G, Sabanayagam C. J Diabetes. 2017 Feb;9(2):200-207.• Evaluation of a training programme to induct medical students to deliver public health talks. Tan NC, Mitesh S, Koh YL, Ang SB, Chan HH, How CH, Tay EG, Hwang SW. Singapore Med J. 2017; 58(1): 35-40.• Pilot Evaluation of a Dementia Case Finding Clinical Service Using the Informant AD8 for At-Risk Older Adults in Primary Health Care: A Brief Report. Shaik MA, Khoo CH, Thiagarajah AG, Tan NC, Li-Hsian Chen C, Xu J, Dong Y. J Am Med Dir Assoc. 2016 Jul 1;17(7):673.e5-8. JIF 4.939• A narrative review of the evaluation and selection of instruments which assess self-efficacy amongst patients with essential hypertension. Lua AYH, Hong L, Bong SHS, Yeo JLS, Tsang MLP, Ong KZ, Wong SSW, Tan NC. Proceedings of Singapore Healthcare. 2016 June. 25(2)• Asian patients with dyslipidemia in an urban population: Effect of ethnicity on their LDL-cholesterol treatment goals. Tan NC, KohKH, Goh CC, Koh YL, Goh SC. J Clin Lipidol. 2016 Mar-Apr 10(2):410-9.• Using a Web-Based Approach to Assess Test-Retest Reliability of the "Hypertension Self-Care Profile" Tool in an Asian Population: A Validation Study. Koh YL, Lua YH, Hong L, Bong HS, Yeo LS, Tsang LP, Ong KZ, Wong SW, Tan NC. Medicine (Baltimore). 2016 Mar;95(9):e2955.• Ten-year longitudinal study of factors influencing nocturnal asthma symptoms amongst Asian patients in primary care. Tan NC, Nadkarni NV, Lye WK, Sankari U, Nguyen VH. Primary Care Respiratory Medicine. 2015 Oct 29;25:15064.• When the Phone Rings - Factors influencing its Impact on the Experience of Patients and Healthcare Workers during primary care consultation: A Qualitative Study. Koong AYL, Koot D, Soo KE, SIngarasoo APR, Yusoff AM, Goh CC, Teo SSW, Tan NC. BMC Family Practice. 2015 Sep 2;16(1):114.• 5-year longitudinal study of determinants of glycemia control for multi-ethnic Asian patients with type 2 diabetes mellitus managed in primary care. Tan NC, Barbier S, Lim WY, Chia KS. Diabetes Research and Clinical Practice. 2015. DOI: 10.1016/j.diabres.2015.07.010• Trends and Predictors of Asthma Costs: Results from a 10-Year Longitudinal Study. European Respiratory Journal. Tan NC, Nguyen VH, Lye WK, Sankari U, Nadkarni NV. Mar 2016 47(3):801-9.• Cross-cultural measurement equivalence of the 5-level EQ-5D (EQ-5D-5L) in patients with type 2 diabetes mellitus in Singapore. Wang Y, Tan NC, Tay EG, Thumboo J, Luo N. Health Qual Life Outcomes. 2015;13(1):103• Comparative immunogenicity and safety of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine and HPV-6/11/16/18 vaccine administered according to two- and three-dose schedules in girls aged 9-14 years: results to month 12 from a randomized trial. Leung TF, Liu AP, Lim FS, Thollot F, Oh HM, Lee BW, Rombo L, Tan NC, Rouzier R, Friel D, De Muynck B, De Simoni S, Suryakiran P, Hezareh M, Folschweiller N, Thomas F, Struyf F. Hum Vaccin Immunother. 2015 Jun 10:0. [Epub ahead of print]• Short-term trajectories of use of a caloric-monitoring mobile-phone application among patients with type 2 diabetes mellitus in a primary care setting. 54. Goh G, Tan NC, Malhotra R, Padmanabhan U, Barbier S, Allen J, Ostbye T. Journal of Medical Internet Research. Feb 2015; 17(2):e33.• Anthropometric indices of obesity and all-cause and cardiovascular disease-related mortality in an Asian Type 2 diabetic population. RBT Lim, C Chen, N Naidoo, G Gay, WE Tang, D Seah, R Chen, NC Tan, J Lee, ES Tai, KS Chia, WY Lim. Diabetes Metab. 2015 Sep;41(4):291-300.• Subjects with colour vision deficiency in the community: what do primary care physicians need to know? Chan XBV, Goh SMS, Tan NC. Asia Pac Fam Med. 2014; 13(10).• Understanding patients' perspective of statin therapy: can we design a better approach to the management of dyslipidaemia? A literature review. Chee YJ, Chan V, Tan NC. Singapore Med J. 2014 Aug;55(8):416-21.• Developing a primary care research agenda through collaborative efforts – a proposed “6E” model. Tan NC, Ng CJ, Rosemary M, Wahid K, Goh LG. Asia Pacific Family Medicine. 2014 Dec 20;13(1):17. Doi:10.1186/s12930-014-0017-9.• Smoking behaviour of Asthmatic patients in primary care continue to smoke- A cross sectional survey. Teo SSH, Tan NC, Ngoh ASH, Swah TS, Chen Z, Tai BC. Proceedings of Singapore Healthcare. 23(2): 108-117.• PAIR UP for primary care excellence: perspective from a primary healthcare provider in Singapore. Tan NC. Singapore Med J. 2014 Mar;55(3): 110-6.• The use of facemask to prevent respiratory infection: a literature review in the context of the Health Belief Model. SW Sim, KSP Moey, Tan NC. Singapore Med J. 2014 Mar;55(3):160-7.• Colour Vision Deficiency: Is it a handicap? A Narrative Review of its Impact on Medical & Dental Education and Practice. Goh SSM, Chan VXB, Tan NC. Proceedings of Singapore Healthcare. 23(2): 149-157.• The influence of caregiver’s knowledge and understanding of asthma etiology on domiciliary management of children with asthma. Soo WF, Tan NC. Singapore Med J. 2014 Mar;55(3):132-6.• How do Primary Care Physicians in Singapore keep themselves healthy? Tan NC, Aw L, Khin LW, Thirumoorthy T, Lim SH, Tai BC, Goh LG. Singapore Med J. 2014 Mar;55(3):155-9.• Effects of a written asthma action plan on caregivers' management of children with asthma: a cross-sectional questionnaire survey. Tan NC, Chen ZJ, Soo WF, Ngoh ASH, Tai BC. Primary Care Respiratory Journal. Apr 2013. 22(2):198-194.• Delivering health talks to public in primary care setting: a novel approach to induct medical students towards social responsibility and health advocacy. Tan NC, How CH, Shah M, Hwang SW, Chee YJ, Tay EG. Med Sci Educator. 2013;23(4):587.• Research consultation clinic: impetus towards facilitating primary care research. Tan NC, Tan YT, Kin PT. Asia Pac Family Med. 2013;12(1):4.doi;10.1186/1447-056X-12-4.• The novel "Prepare-Intensive Coaching -Compete (PICC) model to learn research. Tan NC, Ng CJ. Education for Primary Care. 2012; 23(2): 120-124.• The impact on cigarette smoking on symptoms and quality of life of adults with asthma managed in public primary care clinics in Singapore. Tan NC, Ngoh SHA, Teo SHS, TS Swah, Chen ZJ, Tai BC. Primary Care Respiratory Journal. 2012;21(1): 90-93 Doi:10.4104/pcrj.2012.00003.• Effective communication with hearing impaired patients: An approach for family physicians. Tan TS, Lim CY, Low WK, Tan NC. The Singapore Family Physician. 2011 Mar: 37(1): 61-66.• Initiation of insulin for type 2 diabetes mellitus patients: what are the issues? A qualitative study. Tan AM, Muthusamy L, Ng CC, Phoon IKY, Ow JH, Tan NC. Singapore Med J. 2011 Nov;52(11):801-9. • Treat-to-target approach in managing modifiable risk factors of patients with coronary heart disease in primary care in Singapore: what are the issues? Tan NC, Ho SCW. Asia Pacific Family Medicine. 2011 10;12. Doi:10.1186/1447-056X-10-12.• A qualitative study of parental use of written asthma action plan for their children in Singapore. Journal of Asthma & Allergy Educators. Tan NC, Soo WF, Ngoh ASH. August 2011 2: 185-188, doi:10.1177/2150129711415850.• Lifestyle modifications of patients with coronary arterial disease on follow-up in public primary care centres in Singapore: Assessment of perception and behaviour. Tan NC, Ho CWS, Cheah SL. SFP. 2011; 37(1): 69-72.• Validity and reliability of the Bengali version of the Hepatitis Quality of Life Questionnaire. Chen ZJ, Mamun AM, Rahman S, Tan NC, Luo N, Tai BC. Quality of Life Research. 2010;19:1343-1348.• The inaugural primary care research championship as a social experiment to promote research. Tan NC, Ng CJ, Goh LG. SFP. 2010; 36 (4): 44-5.• COPD management in primary care: What are the issues and what we can do to provide optimal care? Chang NKC, Hii KJ, Chan VHH, Ng CW, Tan NC. The Singapore Family Physician. 2009;35(4); 44-7.• A qualitative study of factors influencing family physicians' prescription of the Written Asthma Action Plan in primary care in Singapore. Tan NC, Tay IH, Ngoh A, Tan M. Singapore Med J. 2009 Feb;50(2):160-4.• Factors influencing family physicians’ drug prescribing behavior in asthma management in primary care. Tan NC, Tay IH, Ngoh A, Tan M. Singapore Med J. 2009; 50(3): 312-9.• Impact of the Singapore National Asthma Program (SNAP) on preventor-reliever prescription ratio in polyclinics. Chong PN, Tan NC, Lim TK. Ann Acad Med Singapore. 2008 Feb;37(2):114-7.• Patients with chronic hepatitis B infection: what is their quality of life? Tan NC, Teo EK, Cheah SL, Yang LH. Singapore Med J. 2008; 49(9): 682-7.• Factors influencing women undertaking screening mammography in primary care in Singapore. Yin LY, Wai KL, Chuan TN, Ghani RBA. Singapore Nursing Journal. 2007:34(3):74-80.• A qualitative study of health-seeking behavior of Hepatitis B carriers. Tan NC, Cheah SL, Teo EK, Violet Kwok. Asia Pac Fam Med. 2005 Jan;46(1):6.• Evaluation of Playground Injuries based on ICD, E codes, International Classification of External Cause of Injury codes (ICECI), and Abbreviated Injury Scale coding systems. Tan NC, Ang A, Heng D, Chen J, Wong HB. Asia Pac J of Public Health. 2007;19(1):87-91.• Chronic disease management in Singapore polyclinics. Lee VKM, Tan NC, Chow MH. Malaysian Family Physician. 2006 Jan;1(2-3):94-96.• Family Physicians’ Experiences, Behavior, And Use of Personal Protection Equipment During The SARS Outbreak in Singapore: Do They Fit The Becker Health Belief Model? Tan NC, Goh LG, Lee SS. Asia Pac J of Public Health. 2006;18(3):49-56.• Use of low calorie sweetener amongst type 2 diabetes patients in an Asian population. Tan NC, Ken G. Asia Pacific Family Medicine. 2006.• ICECI in the real world- Singapore. Tan NC, Ang A, Heng D et al. Injury Issues Monitor 2005 Feb: 32:14-16.• A case study of a woman with statin-related myositis. Wang TT, Tan NC. The Singapore Family Physician 2005; 31(2):54-59• A qualitative study of health-seeking behaviour of Hepatitis B carriers. Tan NC, Cheah SL, Teo EK. Singapore Med J. 2005 Vol 46(1):6-10.• Home blood pressure monitoring amongst hypertensive patients in an Asian population. Tan NC, Khin LW, Pagi R. J Hum Hypertension. 2005; 19(7):559-564.• What barriers do primary care physicians face in the management of patients with chronic hepatitis B infection in primary care? Tan NC, Cheah SL. Singapore Med J. 2005 Jul;46(7):333-9.• What are the barriers faced by doctors in the management of erectile dysfunction in general practice? Tan NC, Ng CJ, Low WY, Choo WY. Asia Pacific Family Medicine 2004;4: 1-6• How Do General Practitioners Improve Compliance of Disease Monitoring by Patients with Chronic Hepatitis B Infection in Primary Care? A Qualitative Study. NC Tan, SL Cheah. Asia Pacific Family Medicine;2004 Jan. Vol. 3:29-37.• Diagnosis and misdiagnosis of hemifacial spasm: a clinical and video study. Tan NC, Tan EK, Khin LW. J Clin Neurosci. 2004 Feb;11(2):142-4.• Management of erectile dysfunction: barriers faced by general practitioners. Low WY, Ng CJ, Tan NC, Choo WY, Tan HM. Asian J of Androl. 2004 Jun;6(2):99-104.• Effectiveness of nurse counseling in discouraging the use of the infant walkers. Tan NC, Lim NM, Gu K. Asia Pacific J Public Health. 2004;16(2):104-8.• The roles of general practitioners in the management of erectile dysfunction-a qualitative study. Ng CJ, Low WY, Tan NC, Choo WY. Int J of Impot Res. Jan 2004; 16(1):60-63.• Factors influencing caregiver's use of an infant walker. Tan NC, Lim LH, Gu K. Asia Pac Fam Med. 2003 March; 2(1); 16-22• A case study of SARS in general practice presenting as biphasic fever. Goh LG, Tan NC, A Wilder-Smith. The Singapore Family Physician. 2003 Oct-Dec; 29(4);96-99.• A case of a man who returned from abroad with fever. Vasanwala F, Tan NC, Chen CL. The Singapore Family Physician, Oct-Dec 2003; Vol. 29(4):93-95.• RETHINK – An observational cross-sectional study on the uptake of insulin therapy among type 2 diabetes patients with secondary drug failure treated in primary care. Tan NC, Tan AM, Yeo JP and RETHINK Study Group. Asia Pacific Family Medicine; 2003 (2):157-165.• Primary care doctors' practice in the management of adult asthma patients. Tan NC, Chow MH, Goh P, Goh LG, Lim TK. Singapore Med J. 2002 Feb;43(2):061-6.• Piloting an Asia Pacific Research Forum (pASPAREF). Tan NC, Ng CJ, Ng M. Letter to editor. Asia Pac Fam Med. 2002 Aug; 1(2/3); 110.• Hemifacial Spasm and Involuntary Facial Movements. Tan NC, Chan LL, Tan EK. QJM 2002; 95: 493-500.• Research Directions. Chuan TN. The Singapore Family Physician. Jul-Sep 2001;27(3):63-67.• Primary care research--a blueprint for action for Singapore. Chuan TN, Gan GL. Asia Pac J Public Health. 2001;13(1):49-53.
Funded Projects:• Improving Screening for Diabetic Maculopathy in primary Care Setting by Combining Digital Fundus Photography and Spectral Domain Optical Coherence Tomography [R1068/83/2013]• Deep Learning System to Analyze Retinal Changes in Patients with Clinical Disease Outcomes [R1522/21/2018]• TRIUMPH: Team-care to Reduce resistance to Insulin initiation Using a new care Model to engage T2D Patients to achieve optimal Health Outcome• The Clinical and Economic Effectiveness of Extending Diabetic Eye Screening in Singapore [R1306/112/2015]• The Singapore Diabetes Complications Study: Closing the Screening - Referral Uptake Loop for Diabetic Retinopathy, Nephropathy, and Foot Complications [R1384/70/2016]• Deep Learning System to Analyze Retinal Changes in Patients with Clinical Disease Outcomes [R1522/21/2018]• Home Blood Pressure Monitoring with Nocturnal Measurement to Control Cardiovascular Risk (Protocol No.: OHQ-CR-160003)• The Clinical and Economic Effectiveness of Extending Diabetic Eye Screening in Singapore [R1306/112/2015]• Developing a Predictive Model for Non-Adherence to Recommended Ophthalmological Referrals in Persons with Diabetes (PM-OR) [1211/17/2015]• HbA1c Variability and Its Association with Diabetic Retinopathy in a Type 2 Diabetic Asian Cohort [R1049/64/2013]• Sustained and White Coat Hypertenion in Primary Care-Diagnosis, Risk Factors and Role of Retinal Vascular Imaging (R910/19/2012)• A Phase IIIb observer-blind, randomnized, multicentre primary immunization study to evaluate the immunogenicity and safety of GSK Biologicals' HPV-16/18 L1 VLP AS04 vaccine and Merck's Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine, when administered intramuscularly according to alternative 2-dose schedules in 9-14 year old healthy females-Protocol No. 115411 (HPV-070 PRI)
Other Projects:• Age-related performance in Adult Asians using a fully-immersive and automated virtual reality system to assess cognitive function• BEdok-Punggol Ongoing Singaporean study beginning in Infancy: Twenty-first century skills, Individual differences, and Variance in the Environment (BE POSITIVE Study)• Barriers to the identification and management of osteoporosis among primary care physicians (PCP) in Singapore• Crisis Management in the Community Mass Recall of Angiotensin II Receptor Blocker Losartan due to Nitrosamine Impurities• IDF-DAR Global Research Survey on diabetes management and complications during Ramadan fasting• COVID-19 Case Series - Critical Data of COVID-19 Patients in the Primary Care Setting• Assessment of a Training programme versus using a manual with an algorithm developed as an Aid to primary care physicians for Spirometry Interpretation• Optimizing care of Patients via Telehealth In Monitoring and Augmenting their control of Diabetes Mellitus (OPTIMUM)• Preferred Role In Shared-Decision Making in Singapore residents (PRISMS)• GLucose Monitoring Programme SingaporE, phase 2 (GLiMPSE2)• A fully-immersive and independent virtual reality system in assessing cognitive function• Impact of a breast cancer survivorship inter-professional community care model (BASIC): a randomised controlled trial• Improving Screening for Diabetic Maculopathy in primary Care Setting by Combining Digital Fundus Photography and Spectral Domain Optical Coherence Tomography [R1068/83/2013]• CAP-DA-GOUT study - Creating a Patient Decision Aid (PDA) for gout treatment• Leveraging AI for Diabetes, Hypertension and HyperLipidemia (DHL) care in the Polyclinics• Awareness and compliance to recommended use of child car restraints in Singapore• COACH Study: Chronic pruritus in older adults - perception, consequences and help-seeking behaviour• Shared decision making in anticoagulation for atrial fibrillation in general practice (SAFE)• To understand how primary care physicians manage patients with multiple medications in Singapore (PRAGMATIC)• A study on the prevalence and factors affecting bone mineral density screening in asymptomatic community dwelling women above 50 years of age at high risk of osteoporosis based on OSTA score• A pilot study evaluating the feasiblity of a patient decision support aid in cervical cancer screening• Effectiveness of diabetes education & medication adjustment with telemonitoring intervention in reducing diabetes complications during Ramadan fasting - a randomized control trial• Postpartum CaRe: Perspectives And praCtices of The prImary CarE physician. (PRACTICE)• A mixed methods study of the common barriers to postpartum diabetes mellitus screening for Singaporean women with a recent history of gestational diabetes mellitus (GDM)• AWESOME Study: AGP for Weight Studies to Optimize Metabolic control. AGP: Ambulatory Glucose Profile, as applied to Continuous Glucose Monitoring (CGM)• A Proof of Concept Study to Test Feasibility and Efficacy of A mHealth System 'MediEasy' on Promoting Medication Adherence of Senior Outpatients with Type 2 Diabetes Mellitus• Deep Learning System to Analyze Retinal Changes in Patients with Clinical Disease Outcomes [R1522/21/2018]• Application and Evaluation of an Artificial Intelligence Deep Learning System to Detect Referable and Sight-threatening Retinal Diseases in the Singapore Integrated Diabetic Retinopathy Screening Programme (SiDRP): Screening Performance and Cost-effectiveness Analysis [R1534/33/2018]• A Randomized Trial to Slow the Progression of Diabetes (The TRIPOD Study)• Glucose Monitoring Programme SingaporE (GLiMPSE)• Feasibility study of using virtual reality in assessing patients with suspected memory disorders• Assessing the risk of coronary artery disease and its association with anxiety disorders amongst patients presenting with chest pain in a primary healthcare setting: a comparison of 3 predictive models• Inappropriate Nephrotoxic Non-Steroidal Anti-Inflammatory Drug in Diabetics, Elderly and Renal Impairment (INSIDER) study.• Issues Faced by Healthcare Providers when Advising Screening Mammography - Perspectives of Healthcare Providers from a Single Government Restructured Primary Healthcare Centre in Singapore• FACET Factors Affecting Complex Patients Enablement: A Qualitative Study• IDEA Study: What are the views of clinicians on the content, design and mode of delivery of an Inhaled corticosteroids patient Decision Aid?• COmplex Patients' Enablement (COPE): A feasibility study to determine the enablement of complex patients in a Multi-disciplinary team (MDT) program.• A Randomized Controlled Trial to Improve Diabetes Outcomes through Financial Incentives. Simplified Title: Trial to Incentivise Adherence for Diabetes (TRIAD).• APN-led chronic disease management to increase patient satisfaction & enablement as a value-add primary care service.(ACHIEVE)• Compatibility between Fasting Cholesterol and Random blood Tests (Comfort trial)• Program for foreign domestic helper to upskill by SHP nurses (Prop up)• Clinical and Cost-effectiveness Analysis on Artificial Intelligence using Deep Learning System for Diabetic Retinopathy Screening• Trial on Weight-Reduction Intervention for Overweight Postnatal Mothers (TRIM)• The views and perceptions of adults, aged 50 years old and above, in Tampines Polyclinic regarding a colorectal cancer screening patient decision aid (PtDA) and how the PtDA influences their decision making and screening behavior.• ANSA - a Feasibility study of an Appointment Notification Smartphone Application customized for patients in a Primary Healthcare setting• VALOUR: Evaluation of a Novel Visual Analogue Uroflowmetry Score (VAUS) to Support Shared Decision-Making for Men with Lower Urinary Tract Symptoms and their Primary Care Physicians• A randomised, double-blind, controlled, multi-centre study to assess the efficacy of an infant formula in the dietary management of infantile colic• TRIUMPH study (TRIUMPH refers to 'Team-based care to Reduce resistance against Insulin initiation Using a new care Model to engage T2D Patients to achieve optimal Health outcomes'.)• To Improve Patient Care and Clinical Outcomes for Asthma and COPD Patients Through Data Linkages and Analytics• App Documentation of Electronic BP readings in Hypertension• Pilot study for the investigation of barriers and facilitators to CKD management faced by patients and healthcare professionals.• Facilitators and barriers in the management of chronic kidney disease faced by patients and healthcare providers. (Quantitative)• MUSCLE-DM study: MUscle Strength in Community Living Elderly with Diabetes Mellitus• MUSCLE-N Study: MUscle Strength in Community Living Elderly (Normal)• A randomized controlled trial to evaluate the health outcomes of patients with stable chronic disease managed with a healthcare kiosk• Unlysed Hyperkalemia - The Unseen Burden (UHUB)• A multicenter, partially-blinded, randomized, 24-week, parallel-group, non-inferiority, open-label active controlled study to compare the efficacy and safety of QVM149 with a free triple combination of salmeterol/fluticasone + tiotropium in patients with uncontrolled asthma• A 2-treatment period, randomized, placebo-controlled, multicenter parallel-group study to assess the safety of QAW039 when added to existing asthma therapy in GINA steps 3, 4 and 5 patients with uncontrolled asthma• PROSPECT: Pcps' Roles, Outlook, Stance, Perspectives in trEating breast cancer survivors: a qualiTative study• Establishing reference range for community dwelling elderly nutrition and a prospective randomized double blind study on the clinical impact of oral nutritional supplement in community-dwelling elderly in Singapore [The NHERC Study]• Factors associated with diabetes-related distress among poorly controlled type 2 diabetics in primary care.• ITICO study: Does Integrated Team-based care Improve Clinical Outcomes.• A single arm feasibility study of GlycoLeap, an on-line lifestyle modification and self-management program for people with Type 2 diabetes.• Poor adherence to antihypertensive medication and its associated factors among hypertensive adults in Singapore: a cross-sectional study• SELf-efficacy in Patients with HYpertension (SELPHY)• Chronic Renal disease Informing Status To Activate Lifestyle changes (CRISTAL): a Pilot Study• Development of Data and Text Algorithms For Signaling Potential Drug-ADR Associations From Electronic Medical Records (EMR) - Using EMR to Evaluate the Safety of Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors Among Patients With Type 2 Diabetes• Psychometric properties of the Medication Adherence Report Scale (MARS-5) in patients with dyslipidemia on statin therapy• Prescription Medication Label Improvement for Singaporean Elderly (PROMISE)• Epidemiology of asthma in Primary care in Singapore• Web-based Intervention for Smoking Elimination (WISE I): Feasibility study• PreDict DM: Pre-Diabetes Initiatives to Curb Transition to Diabetes Mellitus• Determinants of the prevalence and treatment of chronic kidney disease (CKD) in the SingHealth Polyclinics• Home Blood Pressure Monitoring with Nocturnal Measurement to Control Cardiovascular Risk (Protocol No.: OHQ-CR-160003)• Singapore Integrated Diabetic Retinopathy Programme - 5 year retrospective study• Assessment of Willingness to Tele-monitoring Interventions in Patients with Type2 Diabetes and/or Hypertension in the Public Primary Healthcare Setting• A randomised controlled trial to improve hypertension outcomes using wireless home blood pressure monitoring with automatic outcome-based feedback and financial incentives. Simplified title: Wireless monitoring and Financial incentives for uncontrolled HYpertension (WIFHY) trial• The association between illness perceptions, asthma medication beliefs and adherence to inhaled asthma controller among older adults• Diabetes and Health Outcomes study: a retrospective cohort study of type 2 diabetics in the primary care• The update of HBV vaccination amongst seronegative subjects within one year after their HBV serological screening.• The 'Hypertension Self-Care Profile' tool: evaluating its test-retest reliability of its Mandarin & Malay version in an Asian population• The Clinical and Economic Effectiveness of Extending Diabetic Eye Screening in Singapore [R1306/112/2015]• Time Spent in physical and sedentary activities among community-mobile elderly visiting a Singapore government polyclinic. (TiPs - CoME)• Evaluation of a 'hybrid' method to teach dermatology to 3rd year medical students during their primary care attachment• Clinical Evaluation of Biomarkers of Dengue Disease (Protocol No.: EID-DF-CR1)• The Singapore Diabetes Complications Study: Closing the Screening - Referral Uptake Loop for Diabetic Retinopathy, Nephropathy, and Foot Complications [R1384/70/2016]• Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health - A Cluster Randomized Trial in SingHealth Polyclinics, Singapore.• How do Primary Care Physicians in Singapore counsel their obese patients on weight management in general practice? A qualitative study• GOITRE-Gaining our Insight on Thyroxine Replacement• Gout: Quality of Life, Adherence to Medication, self-Efficacy of patients who Reach treatment target (GLAMER)• Developing a Predictive Model for Non-Adherence to Recommended Ophthalmological Referrals in Persons with Diabetes (PM-OR) [1211/17/2015]• Should diabetic patients with non-alcoholic fatty liver disease be screened for severe liver disease and advanced fibrosis?• Patients' attitudes towards deprescribing in public primary healthcare clinics in Singapore.• Factors influencing Drug Adherence among patients with type 2 Diabetes Mellitus (FInD A DM): A qualitative study• Does an inclusive consultation room layout result in better doctor-patient communication?• The effectiveness of strength and balance training in patients with diabetic peripheral neuropathy (DPN) on quality of life (QoL)and functional status: a randomized controlled trial with cost-utility analysis Lay Title: Effect of physical therapy in improving the health of patients with diabetic peripheral neuropathy• Using bioaerosol sampling method to identify infectious airborne viruses in clinical settings.• An International Survey on Hypoglycaemia among Insulin-treated Patients with Diabetes• Uropathogens and antimicrobial susceptibility patterns in urinary tract infections diagnosed in primary care settings• Evaluation of Reinvestment Fund (RF) program to enhance asthma management in SIngHealth Polyclinics• Cross-sectional Study on the Sleeping Patterns and Habits of the General Population• Validation of the 'Hypertension Self-Care Profile' instrument in Multi-ethnic Asian Population• Association between Acquired Colour Vision Impairment (ACVI) and retinal thickness using the Optical Coherence Tomography (SD-OCT) amongst patients with Type 2 Diabetes Mellitus (Phase II)• A case report of a patient who presents with unilateral Hand Tremor and its impace on her quality of life• Case report of the impact of glycemic control when patient carried out massage at subcutaneous site after insulin administration• A case report if a patient who presents with arteruivenous malformation on the tongue - What are the issues involved?• Cohort study of patients with Chronic Hepatitis B infection in primary care• Novel non-invasive biomarkers for the early detection of breast cancer among women with abnormal mammograms• Insomnia and Healthcare Utilization: A Cross-sectional Study of Two Primary Care Clinics in Singapore• Biomechanical Risks Factors in Trigger Finger• National Polyclinics Attendance Study (NPAS) 2014• The evaluation of FeNO for predicting response to an inhaled corticosteroid in subjects with non-specific respiratory symptoms. Protocol OR 01013.• Master of Medicine (Family Medicine) examination: Assessing its Revelance and Values in Enriching Learning ( MARVEL)- A primary care physician's perspective• NEW HEALTH: NEWly Diagnosed Hypertension: qualitative study to Evaluate patients' Access to community health services, their Literacy of their disease, views on their Treatment and Health-seeking behaviour.• Recce study: Research Consultation Clinic Evaluation study• Association between Acquired Colour Vision Impairment (ACVI) and retinal thickness using the Optical Coherence Tomography (SD-OCT) amongst patients with Type 2 Diabetes Mellitus• General Public Education by Medical Students ( GEMS) Study• Long-term clinical outcomes, cost-of-care, clinical characteristics, re-admission rates, outpatient care and mortality in patients with coronary artery disease or congestive heart failure in Singapore ('SingCLOUD' for Singapore Cardiac Longitudinal OUtcomes Database Study)• Grip strength among older Singaporeans: Reference values, instrument agreement and predicting health outcomes (GRIP)• Lipid HEALTH study: Lipid Health beliefs Affecting Lipid Treatment and Health-seeking behaviour• iPrism Study ('interactive diet and activity tracker': Phone app to Reinforce Individual Self-Management)• Intraclass cluster correlation for changes in Blood Pressure and Cholesterol levels SIngHEalth among hypertension Individuals visiting SingHealth Polyclinics - A retrospective review of data for designing cluster studies• HbA1c Variability and Its Association with Diabetic Retinopathy in a Type 2 Diabetic Asian Cohort [R1049/64/2013]• Health-related Quality of Life in the Primary Care Elderly Population with Multiple Morbidity• Prevalence of Orthostatic (Postural) Hypotension among elderly patients aged 65 years and more with chronic diseases attending a polyclinic in Singapore• Association between Acquired Colour Vision Impairment (ACVI) and retinal thickness using the Optical Coherence Tomography (SD-OCT) amongst patients with Type 2 Diabetes Mellitus• Management of Hypertension and multiple risk factors to Enhance Cardiovascular Health - A Cluster of Randomized Trial in SingHealth Polyclinics pilot study• BE KIND ' Behaviour, Experiences, Knowledge and Information needed by Newly-diagnosed (type 2) Diabetic patients'• Prevalence of peripheral neuropathy amongst patients with Vitamin B12 deficiency• Asthma Self-management Phone Intervention Research (ASPIRE Study)• Assessing Acquired Colour Vision Impairment (ACVI) amongst patients with type 2 Diabetes Mellitus (ACVI-DM study)• Impact of phone usage during primary care consultations• Sustained and White Coat Hypertenion in Primary Care-Diagnosis, Risk Factors and Role of Retinal Vascular Imaging (R910/19/2012)• Direct Observed Therapy Study - a Commitment to Opitmize the Management of Tuberculosis (DOTCOMT): Understanding the socioeconomic impact and quality of life of patients with tuberculosis undergoing DOT in primary care in Singapore.• A double blind, double dummy, randomised, multi-centre study to assess the tolerability and efficacy profile of vildagliptin compared to gliclazide as dual therapy with metformin in Muslim patients with type 2 diabetes fasting during Ramadan. Protocol No CLAF237A2411• A Phase IIIb observer-blind, randomnized, multicentre primary immunization study to evaluate the immunogenicity and safety of GSK Biologicals' HPV-16/18 L1 VLP AS04 vaccine and Merck's Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine, when administered intramuscularly according to alternative 2-dose schedules in 9-14 year old healthy females-Protocol No. 115411 (HPV-070 PRI)• The Effects of Internet use on primary health care: patient's perspective• Longitudinal follow-up of cardiac patients using the clinical and administrative databases• NICE Study (Northeast Singapore Infant Cohort Epidemiology Study): A prospective cohort study of common childhood illnesses in primary care in Singapore• Pediatric asthma care and education (PEACE) study• Evaluation of COPD Questionnaire and FEV1/FEV6 as screening tools for diagnosis of COPD in primary care• Relationship between asthma control and patient's attitude, self-efficacy and compliance (CASEC study)• Dietary, Health and Genetic Factors for Parkinson's Disease in the Singapore Chinese Health Cohort Study
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