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Dr Tan Hon Sen Paul

Dr Tan Hon Sen Paul

BSc (Hons), MD, MMed (Anaes)

Associate Consultant

KK Women's and Children's Hospital

Specialty: Women's Anaesthesia

Conditions Treated by this Doctor:
Labour Pain, Obstetric and Gynecologic Surgery, Postoperative Pain.

Clinical Appointments

  • Associate Consultant Women's Anaesthesia KK Women's and Children's HospitalKK Women's and Children's Hospital

Profile

Dr Paul Tan Hon Sen is an Associate Consultant at the Department of Women's Anaesthesia, KK Women’s and Children’s Hospital (KKH).

Dr Paul Tan received his medical degree from Duke-NUS Medical School, Singapore. Subsequently, he completed his specialist training in Anaesthesiology in Singapore, followed by a fellowship at Duke University Hospital, USA. He has been awarded several clinical research grants, including the DREAM Innovation Grant (Duke University), Clinician Scientist Seed Grant (MOH, Singapore), and Pilot Research Grant (SingHealth, Singapore).

He has a keen interest in postoperative pain research and medical device innovation.

Education

  • MMED Anaesthesiology (Singapore) 2017
  • MD (Singapore) 2013
  • BSc. Biological Sciences (Singapore) 2009

Professional Appointments and Committee Memberships

  • Adjunct Research Fellow, Duke-NUS Medical School
  • Associate Consultant, Department of Women’s Anaesthesia, KK Women’s and Children’s Hospital 2020 - Present

Awards

Research Interests

  • Postoperative acute and chronic pain
  • Medical device innovation

Publications

  • The next generation of antiemetics for the management of postoperative nausea and vomiting. Tan HS, Dewinter G, Habib AS. Best Practice and Research Clinical Anaesthesiology (2020) Article in press. (https://doi.org/10.1016/j.bpa.2020.11.004)
  • The effects of labor on airway outcomes with Supreme laryngeal mask in women undergoing cesarean delivery under general anesthesia: a cohort study. Lim MJ, Tan HS, Tan CW, Li SY, Yao WY, Yuan YJ, Sultana R, Sng BL. BMC Anesthesiology (2020) 20:213. (https://doi.org/10.1186/s12871-020-01132-5)
  • Correlation of patient characteristics with arm and finger measurements in Asian parturients: a preliminary study. Lim MJ, Tan CW, Tan HS, Sultana R, Eley V, Sng BL. BMC Anesthesiology (2020) 20:218. (https://doi.org/10.1186/s12871-020-01131-6)
  • The association between preoperative pain catastrophizing and chronic pain after hysterectomy - secondary analysis of a prospective cohort study. Tan HS, Sultana R, Han NLR, Tan CW, Sia ATH, Sng BL. Journal of Pain Research (2020) 13:2151. (https://dx.doi.org/10.2147%2FJPR.S255336)
  • A risk score for postoperative nausea and vomiting in women undergoing cesarean delivery with intrathecal morphine. Tan HS, Cooter M, George, RB, Habib AS. International Journal of Obstetric Anesthesia (2020) 44:126-130. (https://doi.org/10.1016/j.ijoa.2020.08.008)
  • Prediction of breakthrough pain during labour neuraxial analgesia: comparison of machine learning and multivariable regression approaches. Tan HS, Liu N, Sultana R, Han NLR, Tan CW, Zhang J, Sia ATH, Sng BL. International Journal of Obstetric Anesthesia (2020) Article in press. (https://doi.org/10.1016/j.ijoa.2020.08.010)
  • Perioperative factors associated with sub-acute pain after childbirth. Tan HS, Tan CW, Sultana R, Shah M, Leong WL, Sng DD, Sia ATH, Sng BL. Regional Anesthesia and Pain Medicine (2020) 45:1017-1018. (http://dx.doi.org/10.1136/rapm-2020-101750)
  • Association of renin-angiotensin-aldosterone system genetic polymorphisms with maternal hypotension during spinal anaesthesia for caesarean delivery - a retrospective cohort study. Tan HS, Gan YT, Tan EC, Nagarajan S, Sultana R, Han NLR, Sia ATH, Sng BL. International Journal of Obstetric Anesthesia (2020) 44:3-12 (https://doi.org/10.1016/j.ijoa.2020.06.005)
  • Quadratus lumborum block for postoperative analgesia after cesarean delivery: a systematic review with meta-analysis and trial-sequential analysis. Tan HS, Taylor C, Weikel D, Barton K, Habib AS. Journal of Clinical Anesthesia (2020) 67:110003 (https://doi.org/10.1016/j.jclinane.2020.110003)
  • The optimum management of nausea and vomiting during and after cesarean delivery. Tan HS, Habib AS. Best Practice and Research Clinical Anaesthesiology (2020) Article in press. (https://doi.org/10.1016/j.bpa.2020.04.012)
  • Comparison of Supreme laryngeal mask airway versus endotracheal intubation for airway management during general anesthesia for cesarean section: a randomised controlled trial. Yao WY, Li SY, Yuan YJ, Tan HS, Han NL, Sultana R, Assam PN, Sia ATH, Sng BL. BMC Anesthesiology (2019) 19:123. (https://doi.org/10.1186/s12871-019-0792-9)
  • Association of Mallampati scoring on airway outcomes in women undergoing general anesthesia with Supreme laryngeal mask airway in cesarean section. Tan HS, Li SY, Yao WY, Yuan YJ, Sultana R, Han NL, Sia ATH, Sng BL. BMC Anesthesiology (2019) 19:122. (https://doi.org/10.1186/s12871-019-0796-5)
  • Reducing breakthrough pain during labour analgesia: an update. Tan HS, Sng BL, Sia ATH. Curr. Opinion in Anaesthesiology (2019) 32:307-314. (https://doi.org/10.1097/ACO.0000000000000713)
  • Closed-loop double-vasopressor automated system vs manual bolus vasopressor to treat hypotension during spinal anaesthesia for caesarean section: a randomised controlled trial. Sng BL, Tan HS, Sia ATH. Anaesthesia (2014) 69(1):35-45 (https://doi.org/10.1111/anae.12460)
  • Control of blood pressure during spinal anaesthesia for caesarean section. Tan HS, Sng BL. Trends in Anaesthesia and Crit. Care (2013) 3:166-170 (https://doi.org/10.1016/j.tacc.2013.02.010)
  • Interactive technology in obstetric anaesthesia and analgesia: exploring seamless solutions to jagged problems. Sia ATH, Sng BL, Tan HS. International Journal of Obstetric Anesthesia (2013) 22(4):322-8 (https://doi.org/10.1016/j.ijoa.2013.07.004)
  • Closed-loop double vasopressor automated system to treat hypotension during spinal anaesthesia for Caesarean section: a preliminary study. Sia ATH, Tan HS, Sng BL. Anaesthesia (2012) 67(12):1348-55 (https://doi.org/10.1111/anae.12000)
  • Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK. Molecular and Cellular Proteomics (2010) 9:1085-1099. (https://doi.org/10.1074/mcp.M900381-MCP200)

Research Trials

  • DREAM Innovation Grant (Co-Investigator)
    Duke University, Durham, USA 2019 - 2021
    Role of CSF and serum biomarkers and neuroinflammation in chronic pain and perinatal depression after cesarean delivery.
  • Clinician Scientist Seed Grant (Principal Investigator)
    Ministry of Health, Singapore 2019 - 2021
    Evaluation of associated perioperative risk factors for chronic post-hysterectomy pain: a prospective cohort study. (EPOCH: Enhancing Postoperative Outcomes in Chronic pain after Hysterectomy)
  • Pilot Research Grant (Principal Investigator)
    SingHealth Anaesthesiology Academic Clinical Program, Singapore 2017 - 2018
    The role of angiotensin genetic polymorphism in predicting the risk of hypotension during spinal anaesthesia for caesarean delivery.