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Dr Ngo Nye Thane

Dr Ngo Nye Thane

​FRCPath (UK), MRCP(UK), MBBS, Postgrad Dip of Law

Consultant

Specialty: Pathology

Clinical Interest: Uropathology, Gastrointestinal Pathology

Clinical Appointments

  • Consultant Anatomical Pathology Singapore General HospitalSingapore General Hospital
  • Pathology Team Inflammatory Bowel Disease Centre Singapore General HospitalSingapore General Hospital

Profile

​Dr Ngo Nye-Thane is a Consultant with the Department of Pathology at the Singapore General Hospital. Her specialty interests are in gastrointestinal pathology and uropatholocy.

Education

  • ​MBBS: Royal Free and University College London Medical School (2000) 
  • Postgraduate Diploma of Law with Commendation: College of Law (2002) 
  • MRCP: Royal College of Physicians (2005) 
  • FRCPath: Royal College of Pathologists (2011)

Professional Appointments and Committee Memberships

Awards

  • ​1996: Cayley Prize for Excellence in Biochemistry 
  • 2008: RCS Norman Tanner award presentation 
  • 2010: 1st Prize Northwest Thames Histopathology Trainee Presentation Day


Research Interests

  • OCT scanning of fresh prostate tissue for real time staging of prostate cancer - Feasibility study 
  • INDEX (Focal Hifu): A Multi-centre Prospective Single Arm Intervention Trial Evaluating Focal Therapy using High Intensity Focused Ultrasound (Sonablate 500) for Localised Prostate Cancer 
  • PROMIS: Prostate MRI Imaging Study (MRC PR11) . Evaluation of Multi-Parametric Magnetic Resonance Imaging in the Diagnosis and Characterisation of Prostate Cancer 
  • Prostate Histoscanning PHS-02: Prostate Histoscanning for the non-invasive detection and staging of prostate cancer and characterization of prostate tissues. The PHS-02 Study 
  • Tractomap study: Correlation of neurovascular bundles between prostate MRI scanning and histopathology 

Publications

  • An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes.
    Pinato DJ, Tan TM, Toussi ST, Ramachandran R, Martin N, Meeran K, Ngo N, Dina R, Sharma R.
    Br J cancer 2013 Nov 14
  • Tumour-to-tumour metastases: prostate carcinoma metastasising to a renal oncocytoma.
    Petts G, Rashid T, Hrouda D, Ngo NT; BMJ Case Rep. 2013 Jan 9
  • Immunohistochemical markers of the hypoxic response can identify malignancy in phaeochromocytomas and paragangliomas and optimize the detection of tumours with VHL germline mutations.
    Pinato DJ, Ramachandran R, Toussi ST, Vergine M, Ngo N, Sharma R, Lloyd T, Meeran K, Palazzo F, Martin N, Khoo B, Dina R, Tan TM; Br J Cancer 2013 Feb 5; 108 (2): 429-37
  • Meta-analysis: sacral nerve stimulation versus conservative therapy in the treatment of faecal incontinence.
    Tan E, Ngo NT, Darzi A, Shenouda M, Tekkis PP; Int J Colorectal Dis. 2011 Mar;26(3):275-94
  • Differential expression of p53 and p504s in hyperplastic polyp, sessile serrated adenoma and traditional serrated adenoma.
    Ngo NT, Tan E, Tekkis P, Peston D, Cohen P; Int J Colorectal Dis. 2010 Oct;25(10):1193-200
  • The significance of tumour cell immunophenotype in myeloma and its impact on clinical outcome.
    Ngo NT, Brodie C, Giles C, Horncastle D, Klammer M, Lampert IA, Rahemtulla A, Naresh KN|
    J Clin Pathol. 2009 Nov;62(11):1009-15.
  • Correlation of cyclin D1 transcript levels, transcript type and protein expression with proliferation and histology among mantle cell lymphoma.
    Shakir R, Ngo N, Naresh KN; J Clin Pathol. 2008 Aug;61(8):920-7
  • Bone marrow trephine morphology and immunohistochemical findings in chronic myelomonocytic leukaemia.
    Ngo NT, Lampert IA, Naresh KN; Br J Haematol. 2008 Jun;141(6):771-81
  • Bone marrow trephine findings in acute myeloid leukaemia with multilineage dysplasia.
    Ngo N, Lampert IA, Naresh KN; Br J Haematol. 2008 Feb;140(3):279-86
  • Leucocyte common antigen (CD45) and CD5 positivity in an "undifferentiated" carcinoma: a potential diagnostic pitfall.
    Ngo N, Patel K, Isaacson PG, Naresh KN; J Clin Pathol. 2007 Aug;60(8):936-8
  • Enterocolic lymphocytic phlebitis: clinicopathologic features and review of the literature.
    Ngo N, Chang F; Arch Pathol Lab Med. 2007 Jul;131(7):1130-4

 

Oral Presentations

 

International:

 

  • European Society of Coloproctology annual meeting, Copenhagen (Sept 2011)
    "Prucalopride versus placebo in the treatment of chronic constipation - a meta analysis"
    E Tan, J Hodgkinson, N Ngo, A Darzi, P Tekkis

 

National:

 

  • British Endocrine Symposium, Harrogate (March 2012)
  • “Role of the hypoxic signalling pathways in the histopathological prediction of malignancy in phaeochromocytomas and paragangliomas”
    D. J. Pinato, R. Ramachandran, S. T. K. Toussi, M. Vergine, N. Ngo, R. Sharma, T. Lloyd, K. Meeran, F. Palazzo, N. Martin, R. Dina, T. M. Tan
    RCS Norman Tanner award presentation (Shortlisted), 2008
  • “Sacral Nerve Stimulation versus conservative therapy for the treatment of faecal incontinence – a meta-analysis”
    E Tan , M Shenouda, NT Ngo, PP Tekkis

Hospital:

  • Case presentation of an anaemic patient
    Barnet General Hospital (June 2003)
    “Multiple Endocrine Neoplasia – a case presentation (April 1998)”
    University College London Grand Round (April 1998)

 

 

 

Poster Presentations

 

International:

 

  • International Academy of Pathology (Oct 2008)
    “ Differential expression of p53 and P504S in sessile serrated polyps and traditional serrated adenomas as markers of malignant potential”
    Ngo NT, E. Tan, P. Tekkis, D. Peston, P. Cohen 
  • Disease Week, San Diego, USA (May 2008)
    “ Differential expression of p53 and P504S in sessile serrated polyps and traditional serrated adenomas as markers of malignant potential”
    Ngo NT, E. Tan, P. Tekkis, D. Peston, P. Cohen 

 

 

National:

 

  • British Society for Haematology (April 2008)
    “The clinical impact of tumour cell immunophenotype in multiple myeloma”
    Ngo N, D. Horncastle, C. Giles, I.A. Lampert, A. Rahemtulla, K.N. Naresh 
  • British Society for Haematology (April 2007)
    “Bone marrow trephine findings in CMML”
    Ngo N, Lampert IA, Naresh KN
  • British Society for Haematology (April 2007)
    “Bone Marrow Trephine Findings In AML With Multi-lineage Dysplasia”
    Ngo N, Lampert IA, Naresh KN

 

 

 

 


Research Trials