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Dr Lim Hsuen Elaine

Dr Lim Hsuen Elaine from National Cancer Centre Singapore

Dr Lim Hsuen Elaine

MBBCh (Cantab), MRCP (UK), MRCP (London), MA, PhD (Cantab), FAMS

Senior Consultant

National Cancer Centre Singapore

Specialty: Medical Oncology

Sub-specialties: Gynae-Oncology, Breast

Conditions Treated by this Doctor:
Breast Cancer , Gynaecology.

Clinical Appointments

  • Senior Consultant Division of Medical Oncology National Cancer Centre SingaporeNational Cancer Centre Singapore
  • Director Division of Community Outreach and Philanthropy National Cancer Centre SingaporeNational Cancer Centre Singapore

Profile

Dr Elaine Lim is Senior Consultant, Division of Medical Oncology at the National Cancer Centre, Singapore. Her interests are centred on breast, gynaecological and lung cancers. 

After graduating from Trinity College, University of Cambridge, Dr. Lim was selected to join the Cambridge MBBCh-PhD programme. Her PhD dissertation on molecular genetics was supervised by Nobel Laureate, Professor Sydney Brenner and Professor Timothy Cox. After completing her clinical training in Cambridge, Dr. Lim worked in London, which included the Royal London Hospital and the prestigious London ‘golden circuit’ of Hammersmith Hospital and Royal Brompton Hospital. 

Upon her return to Singapore, she joined the National University of Singapore (NUS) and National University Hospital (NUH) to pursue a career in Medical Oncology. She later moved to Johns Hopkins Singapore as Consultant in Medical Oncology, as well as being Visiting Consultant at Tan Tock Seng Hospital (TTSH) and Kandang Kerbau Women’s and Children’s Hospital (KKH). After a few years in private practice with Singapore Oncology Consultants, she joined the National Cancer Centre, Singapore, Division of Medical Oncology. She has continued her laboratory research activities in collaboration with the Genome Institute of Singapore and the Institute of Molecular and Cell Biology, and actively participates in clinical trials.

Education

  • University of Cambridge, Trinity College, England

Professional Appointments and Committee Memberships

  • Fellow of Academy of Medicine 
  • ASCO (American Society of Clinical Oncology) 
  • American Association for Cancer Research 
  • Singapore Medical Association 
  • British Medical Association, UK 
  • Royal Society of Medicine, UK 
  • Royal College of Physicians, United Kingdom

Awards

Research Interests

  • Breast Cancer
  • Lung Cancer
  • Gynaecological Cancer
  • Cancer Stem Cells
  • Molecular Signalling Pathways
  • Epigenetics

Publications

  • CD166pos Subpopulation From Differentiated Human ES and iPS Cells Support Repair of Acute Lung Injury. Soh BS, Zheng D, Yeo JS, Yang HH, Ng SY, Wong LH, Zhang W, Li P, Nichane M, Asmat A, Wong PS, et al, Lim EH, Lim B.Molecular Therapy. 2012 Dec;20(12):2335-46. 
  • Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis. Zhang WC, Shyh-Chang N, Yang H, Rai A, Umashankar S, Ma S, Soh BS, Sun LL, Tai BC, Nga ME, Bhakoo KK, et al, Lim EH, Lim B. Cell. 2012 Jan 20;148(1):259-72. 
  • Cervical dysplasia: assessing methylation status (Methylight) of CCNA1, DAPK1, HS3ST2, PAX1 and TFPI2 to improve diagnostic accuracy. Lim EH, Ng SL, Li JL, Chang AR, Ng J, Ilancheran A, Low J, Quek SC, Tay EH. Gynecol Oncol 2010, 119: 225-231. 
  • Pleiotrophin Enhances Clonal Growth and Long‐Term Expansion of Human Embryonic Stem Cells. Soh BS, Song CM, Vallier L, Li P, Choong C, Yeo BH, Lim EH, Pedersen RA, Yang HH, Rao M, Lim B. Stem Cells. 2007 Dec 1;25(12):3029-37. 
  • Oxaliplatin/fluorouracil/leucovorin in advanced colorectal carcinoma: an Asian experience. Lim EH, Lim RS, Wu TS, Kong HL. Annals of Pharmacotherapy. 2003 Dec 1;37(12):1909-12.

Research Trials

  • Breast Cancer: Investigating Carcinogenesis, Cancer Progression and Treatment Resistance 
  • Ovarian Carcinoma - Investigating Treatment Resistance and the Link with Endometriosis Using Molecular Genetics Profiles, Cellular Models and Immunophenotyping