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Dr Kam Li Wei, Michelle

Dr Kam Li Wei Michelle

MBBS, MRCS(Edin), MRCP(UK), MMed

Consultant

Singapore General Hospital

Specialty: Respiratory & Critical Care Medicine

Clinical Interest: Interstitial Lung Disease, Orphan Lung Disease, Sarcoid

Conditions Treated by this Doctor:
Asthma, Birt Hogg Dube, Bronchiectasis, Chronic Obstructive Pulmonary Disease (COPD), Emphyema, Hereditary Hemorrhagic Telangiectasia, Interstitial Lung Disease, Lymphangioleiomyomatosis, Pneumonia, Pulmonary Langerhans Cell Histiocytosis, Sarcoid, Severe Asthma.

Clinical Appointments

  • Consultant Respiratory & Critical Care Medicine Singapore General HospitalSingapore General Hospital

Academic Appointments

  • Physician Faculty, Internal Medicine, Singhealth Residency Program
  • Physician Faculty, Respiratory Medicine. Singhealth Senior Residency Program

Profile

I completed a subspecialty fellowship in Interstitial Lung Disease (ILD) at National Jewish Health, during which I also received training in sarcoidosis and granulomatous lung disease, orphan lung disease, childhood ILD, genetic counselling, and occupational and environmental health medicine. My research interests include high-risk ILD disease types with a focus on genetic and molecular risk profiling. My work has been published in international peer-reviewed journals and presented at international conferences. I have been invited as a faculty member and chairman at international conferences. I have been awarded several research grants as principal investigator and received the inaugural Singapore Thoracic Society Young Investigator’s Award in 2022.

Education

  • M Med (Internal Med)
  • MRCP (UK)
  • MRCS (Edin)
  • MBBS

Professional Appointments and Committee Memberships

  • ​Physician Faculty Member, Singhealth Respiratory Medicine Senior Residency Programme

Awards

  • COVID-19 Resilience Medal and COVID-19 Resilience Certificate (2023)
  • Service with a Heart Award (2023)
  • Singhealth Doctors and Dentists Long Service Award 10 Years (2023)
  • Singapore Thoracic Society Young Investigators’ Award (2022)
  • Singhealth Best House Officer Award (2012)
  • Class of 1975 Book Prize (2010)

Research Interests

  • Interstitial Lung Disease
  • Orphan Lung Diseases
  • Sarcoid
  • Pulmonary Genetics

Publications

  • Kam MLW, Tjong EL, Chaudhary S, Koelsch TL, Pryor JB, Koslow M, Mohning MP, Solomon JJ, Huie TJ, Swigris JJ, Fernández Pérez ER. Development and Validation of a Clinical, CT, Genomic Classifier and BAL Scoring System for Diagnosing IPF. Eur Respir J. 2025 Jan 16:2401077. doi: 10.1183/13993003.01077-2024.
  • Quantitative CT Scan Analysis in Rheumatoid Arthritis-Related Interstitial Lung Disease. SM Humphries, A Adegunsoye, MK Demoruelle, MLW Kam, I Amigues, TJ Bang, SD Teague, DA Lynch, JH Chung, ME Strek, JJ Swigris, JJ Solomon. Chest. 2024 Nov 9:S0012-3692(24)05472-2. doi: 10.1016/j.chest.2024.10.052.
  • First ever characterisation of the effects of short telomeres in a Singapore interstitial lung disease cohort. Kam MLW, Chong ST, Chan SH, Swigris JJ, Chew EL, Tan YH, Ngeow JYY, Low SY. Respir Investig. 2024;62(3):348-355. doi: 10.1016/j.resinv.2024.02.004.
  • The road to hell is paved with good intentions: a look back at the PANTHER-IPF trial. M Kam, J Caliez, H Nunes, T Gille. Breathe 2022 18: 220074; DOI: 10.1183/20734735.0074-2022
  • Cluster phenotypes in a non-idiopathic pulmonary fibrosis fibrotic interstitial lung diseases cohort in Singapore. MLW Kam, PY Tiew, HZ Chai, SY Low. Journal of Thoracic Disease 2022;14(7):2481-2492. https://ddei5-0-ctp.trendmicro.com:443/wis/clicktime/v1/query?url=https%3a%2f%2fdx.doi.org%2f10.21037%2fjtd%2d22%2d40&umid=7969C0B3-2EDE-6606-BC6C-6E09F1DE33C1&auth=47c05c838325d75a419a880435ac0d2beef06415-b5cee1d510c5998f7b16871ccdcb7463806acaf1
  • Country-wide genotyping of Mycobacterium tuberculosis complex in Singapore, 2011-2017. MLW Kam, LKY Lim, LH Sng, RTH Ong, VJM Lee, YT Wang, CBE Chee. Tuberculosis 2022 (134), 102204
  • Telomere Biology Disorders. MLW Kam, TTT Nguyen, JYY Ngeow. npj Genomic Medicine (2021) 6(1):36 ; https://ddei5-0-ctp.trendmicro.com:443/wis/clicktime/v1/query?url=https%3a%2f%2fdoi.org%2f10.1038%2fs41525%2d021%2d00198%2d5&umid=7969C0B3-2EDE-6606-BC6C-6E09F1DE33C1&auth=47c05c838325d75a419a880435ac0d2beef06415-d36bc42d6b2b9b1416a29044e083461ca91a6fe9
  • Validation of the ILD-GAP Model and a local nomogram in a Singaporean Cohort. MLW Kam, HH Li, YH Tan, SY Low. Respiration 2019;98(5):383-390.
  • 2015 Epidemic of Severe Streptococcus agalactiae Sequence Type 283 Infections in Singapore Associated with the Consumption of Raw Freshwater Fish: A Detailed Analysis of Clinical, Epidemiological, and Bacterial Sequencing Data. S. Kalimuddin, S. L. Chen, C. T. K. Lim, T. H. Koh, T. Y. Tan, M. Kam, C. W. Wong, K. S. Mehershahi, M. L. Chau, L. C. Ng, W. Y. Tang, H. Badaruddin, J. Teo, A. Apisarnthanarak, N. Suwantarat, M. Ip, M. T. G. Holden, L. Y. Hsu, T. Barkham, for the Singapore Group B Streptococcus Consortium. Clin Infect Dis 2017; 64 (suppl_2): S145-S152.

Research Trials