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Asst Prof Chua Wei Ling Clarinda

Dr Chua Wei Ling Clarinda from National Cancer Centre Singapore

Asst Prof Chua Wei Ling Clarinda

MBBS, MRCP (UK), MMed (Internal Medicine), MCI 

Senior Consultant

National Cancer Centre Singapore

Specialty: Medical Oncology

Sub-specialties: Colorectal, Upper Gastrointestinal

Conditions Treated by this Doctor:
Colorectal Cancer, Upper Gastrointestinal Cancers.

Clinical Appointments

  • Senior Consultant Division of Medical Oncology National Cancer Centre SingaporeNational Cancer Centre Singapore

Academic Appointments

  • Clinical Lecturer
  • Assistant Professor

Profile

Dr Clarinda Chua is a medical oncologist with a sub-specialty in gastrointestinal cancers / colorectal cancer.

Education

  • Master of Clinical Investigation, National University of Singapore 
  • MMed (Internal Medicine), National University of Singapore 
  • MRCP, Royal College of Physicians, UK
  • MBBS, National University of Singapore 

Professional Appointments and Committee Memberships

  • Member, Academic Medicine Research Institute 
  • Member, Singapore Society of Oncology 
  • Member, Singapore Medical Association

Awards

  • NMRC/MOH Healthcare Research Scholarship (Master of Clinical Investigation, Yong Loo Lin School of Medicine, National University of Singapore) 
  • Best Medical Officer, 2008

Research Interests

  • Cancer metastasis 
  • Colorectal cancer 
  • Gastrointestinal cancer

Publications

  • Tan HL, Chia CS, Tan GH, Choo SP, Tai DW, Chua CW, Ng MC, Soo KC, Teo MC. Gastric peritoneal carcinomatosis - a retrospective review. World J Gastrointest Oncol. 2017 Mar 15;9(3):121-128. 
  • Li H, Courtois ET, Sengupta D, Tan Y, Chen KH, Goh JJ, Kong SL, Chua C, Hon LK, Tan WS, Wong M, Choi PJ, Wee LJ, Hillmer AM, Tan IB, Robson P, Prabhakar S. Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors. Nat Genet. 2017 Mar 20. [Epub ahead of print] 
  • Suzuki Y, Ng SB, Chua C, Leow WQ, Chng J, Liu SY, Ramnarayanan K, Gan A, Ho DL, Ten R, Su Y, Lezhava A, Lai JH, Koh D, Lim KH, Tan P, Rozen SG, Tan IB. Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer. Mol Oncol. 2017 Feb;11(2):124-139. 
  • Ng SB, Chua C, Ng M, Gan A, Poon PS, Teo M, Fu C, Leow WQ, Lim KH, Chung A, Koo SL, Choo SP, Ho D, Rozen S, Tan P, Wong M, Burkholder WF, Tan IB. Individualised multiplexed circulating tumour DNA assays for monitoring of tumour presence in patients after colorectal cancer surgery. Sci Rep. 2017 Jan 19;7:40737.
  • Tan G, Chia C, Kumar M, Choo SP, Chia J, Tham CK, Chua C, Soo KC, Teo M. 201 consecutive cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) procedures in a single Asian tertiary centre. Int J Hyperthermia. 2016 Dec 14:1-7. [Epub ahead of print] 
  • Cima I, Kong SL, Sengupta D, Tan IB, Phyo WM, Lee D, Hu M, Iliescu C, Alexander I, Goh WL, Rahmani M, Suhaimi NA, Vo JH, Tai JA, Tan JH, Chua C, Ten R, Lim WJ, Chew MH, Hauser CA, van Dam RM, Lim WY, Prabhakar S, Lim B, Koh PK, Robson P, Ying JY, Hillmer AM, Tan MH. Tumor-derived circulating endothelial cell clusters in colorectal cancer. Sci Transl Med. 2016 Jun 29;8(345):345ra89. 
  • Fukawa T, Yan-Jiang BC, Min-Wen JC, Jun-Hao ET, Huang D, Qian CN, Ong P, Li Z, Chen S, Mak SY, Lim WJ, Kanayama HO, Mohan RE, Wang RR, Lai JH, Chua C, Ong HS, Tan KK, Ho YS, Tan IB, Teh BT, Shyh-Chang N. Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia. Nat Med. 2016 Jun;22(6):666-71. 
  • Chong DQ, Manalo M, Imperial M, Teo P, Yong G, Ng M, Tan IB, Choo SP, Chua C. Safety and efficacy of aflibercept in combination with fluorouracil, leucovorin and irinotecan in the treatment of Asian patients with metastatic colorectal cancer. Asia Pac J Clin Oncol. 2016 Sep;12(3):275-83. 
  • Wang SR, Malik S, Tan IB, Chan YS, Hoi Q, Ow JL, He CZ, Ching CE, Poh DY, Seah HM, Cheung KH, Perumal D, Devasia AG, Pan L, Ang S, Lee SE, Ten R, Chua C, Tan DS, Qu JZ, Bylstra YM, Lim L, Lezhava A, Ng PC, Wong CW, Lim T, Tan P. Technical Validation of a Next-Generation Sequencing Assay for Detecting Actionable Mutations in Patients with Gastrointestinal Cancer. J Mol Diagn. 2016 May;18(3):416-24. 
  • Chua C, J Raaj, S Pan, M Farid, JFM Lee, ZC Ho, A Sairi, K Sittampalam, M Tao, K Tay, ST Lim, F Chin, M Teo, R Quek. Brain metastasis in sarcoma: Does metastasectomy or aggressive multi-disciplinary treatment improve survival outcomes. Asia Pac J Clin Oncol. 2016 Mar;12(1):e16-22.

Research Trials

  • Study of metastasis in colorectal cancer using patient derived tumor models