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Drug Class: Commonly Known As: Category:
Antifungal Noxafil Children, Adult, Cancer-related

Posaconazole - Side Effects, Precautions, and Contraindications

What side effects can Posaconazole cause?

Some of the common side effects of posaconazole include

  • Stomach discomfort, nausea and vomiting, diarrhea and constipation
  • Low potassium , calcium and magnesium levels resulting in muscle pain and weakness
  • Headache, dizziness or drowsiness.

Please inform your doctor if you experience any other side effects or if the side effects become severe and bothersome.

There are some potentially serious, but less common side effects that may be experienced. If they occur, seek medical attention immediately:

  • Rash and other signs of allergic reactions such as tightness in the chest or throat, trouble breathing, swelling in the mouth, face or lips.
  • Signs of liver problems like dark urine, feeling tired, inability to eat a full meal or feeling full after only a small amount of food, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Fast heartbeat, a heartbeat that does not feel normal, or passing out.

Before taking Posaconazole, what precautions must I follow?

What food or medicine must I avoid when I take Posaconazole?

Before starting posaconazole, do inform your doctor of any other medications that you are already on.

Do not take/give any other medications or herbal products without consulting your doctor or pharmacist. Some medication or food may reduce its efficacy, or increase the incidence of side effects where close monitoring is required. Posaconazole may also increase the side effects of other medications such as cholesterol medications and immunosuppressants. You may also need to avoid antacids or medications that may reduce acidity of the stomach.

Posaconazole - Additional Information

​Do not use this medicine if you are allergic to posaconazole.  Before starting posaconazole, do inform your doctor of any other medications that you are already on. 

Do not take during pregnancy. Effective contraception is advised in females of childbearing potential.

  • Updated on Friday, September 21, 2018
  • Article contributed by Pharmacy Department KK Women's and Children's Hospital

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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