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Drug Class: Commonly Known As: Category:
Chloride Channel Activator Amitiza

Lubiprostone - Side Effects, Precautions, and Contraindications

What side effects can Lubiprostone cause?

Common side effects include:

  • ​Nausea
    • Take this medication with food.
  • Dizziness, fainting or a drop in blood pressure
    • The risk may be increased if you develop diarrhoea or vomiting during treatment. Generally, these side effects go away after some time.
  • Shortness of breath
    • It may occur especially within an hour of the first dose but generally goes away within three hours. It may happen again with repeated doses.
  • Other side effects include stomach discomfort, headaches, sweating and palpitations.

Rare but serious side effects include:

  • Stomach pain or cramps that does not go away, inability to pass gas or stool, fever, vomiting or diarrhea during the treatment.

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Lubiprostone, what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication
  • You are pregnant, planning to become pregnant, or breastfeeding
  • You are taking any other medications, including supplements, traditional medications and herbal remedies
  • You have liver disease

What food or medicine must I avoid when I take Lubiprostone?

​Inform your healthcare professional if you are taking or intend to take any other medication, supplements, traditional medications or herbal remedies.

Lubiprostone - Additional Information

  • Updated on Monday, September 30, 2019
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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