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FAQs on Biologics and Biosimilars

Drug Class: Commonly Known As: Category:
Children, Adult

FAQs on Biologics and Biosimilars - Side Effects, Precautions, and Contraindications

What side effects can FAQs on Biologics and Biosimilars cause?

  • Increased risk of infection such as upper respiratory tract infection (URTI), urinary tract infection (UTI) and skin infections. If you get an infection while on biologic or biosimilar, inform your healthcare professional so it can be treated immediately.

  • Reactivation of certain infectious diseases such as Hepatitis B or Tuberculosis (TB). Your doctor will order tests to assess your risk and decide on treatment before starting a biologic or biosimilar. In addition, your doctor will ensure your vaccination status is updated to further reduce your risk of getting an infection.

  • Allergic reactions such as shortness of breath, chills, itchiness, redness or swelling around the eyes/lips/skin may develop. If you experience any of such symptoms, stop the medicine and see your healthcare professional so it can be treated immediately.
Side effects for biologics and biosimilars ​ ​

Common > 10%

Infection such as cold, upper respiratory infection, sinusitis, mild injection site reactions such as redness and pain

Uncommon 1-3%

Severe infection require hospitalisation, severe infusion reactions.

Central nervous system reaction such as sudden vision problems or any numbness or tingling.

Cardiac (heart) issues which may manifest as shortness of breath or sudden swelling of the ankles.

Rare < 1 in 1000

Reactivation of Tuberculosis (TB), Shingles, Hepatitis B, cancer of the blood, skin or lung, another immune diseases such as lupus-like syndrome (which may appear as rash that gets worse when exposed to the sun or new joint pains)

Inform your healthcare professional immediately if you experience any of these or other unexplained symptoms.

Before taking FAQs on Biologics and Biosimilars, what precautions must I follow?

What food or medicine must I avoid when I take FAQs on Biologics and Biosimilars?

FAQs on Biologics and Biosimilars - Additional Information

  • Updated on Monday, March 26, 2018
  • Article contributed by Pharmacy Sengkang General Hospital, Singapore General Hospital

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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